Hydrocodone or Hysingla is an analgesic type medication. It comes under the category of opioids and is used in the treatment of severe pain. It is also combined with other compounds, which then are used as cough syrups for adults. Generally, it is found in combination with acetaminophen or ibuprofen. Hydrocodone is available in the market only in the oral forms. It is available in the tablet forms as well as liquid formulations.
Hydrocodone works as a long-lasting medicine if used without combining with other medications. However, the usual dose of Hydrocodone contains the combination of opioid or narcotic and non-opioid or analgesic drugs to increase the work of action. Since it contains analgesic, it also helps to reduce fever along with the pain-relieving effect.
The combination of opioid and non-opioid present inside the Hydrocodone work by acting upon a receptor present inside the brain generally known as GABA receptors. Hydrocodone stimulates them to produce GABA neurotransmitters, which help to relieve pain when present in a sufficient amount.
According to some studies, it takes about 20-30 minutes for Hydrocodone to start its action of work. The medication works for about 4-8 hours, after which its effect begins depleting. So the total working of this medication comes into play for about 4- 8 hours approximately. It is highly recommended to take the next dose only after 4-6 hours.
3.8 hours is the approximate half-life of Hydrocodone, i.e., it takes about an average of 3.8 hours for 50% of this medicine to eliminate from the body. So if calculated according to the half-life, Hydrocodone stays in our system for about 1 or 1 and a half-day.
Hydrocodone was kept under the category of schedule III by the US government. The FDA approved a formulation of Hydrocodone in 2014, but the approval was facing a low time with a lot of controversies going around. The approval was strongly resisted by many panel members of the FDA because, according to them, this formulation had the potential to increase the risk of abuse.
However, the FDA approved this formulation even after the existence of so much resistance.
Today, Hydrocodone is shifted to the stricter category of Schedule II from Schedule III because of the higher risk of abuse as the abuse was more than double during 2011.
Make a note of all your signs and symptoms and consult a doctor positively if these symptoms appear for a longer duration.
Remember to carefully read and follow the safety instructions provided by the pharmacist before you take this medicine.
Hydrocodone is an opioid which shows some substantial effects on the pain. It is possible to get the desired results from Hydrocodone, but it is essential to keep in mind all the side-effects that it may cause.